MDMA Safety and Benefits

The cluster focuses on debates about MDMA's safety, neurotoxicity, addiction risks, therapeutic potential for conditions like PTSD, and its classification relative to psychedelics and other drugs.

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Keywords

PMC5756147 EDM OP MDA www.ncbi PCP MDMC LSD HT2A THAT mdma drugs psychedelics recreational dose ptsd effects doses study brain

Sample Comments

hoseja Nov 14, 2023 View on HN

From what I read, MDMA is barely worse than weed or booze.

openfuture Jun 12, 2018 View on HN

MDMA is not a "proper" psychadelic imo

rubatuga Jun 3, 2024 View on HN

MDMA (what's ecstasy?) could get approval but it could also result in people getting addicted to it. Doesn't take a lot of searching to find stories of people who damage their brains after prolonged usage. I'm sure MDMA has its benefits, but there's probably other risks involved in prescribing it in a healthcare setting. Benzodiazepines were routinely given out by doctors, but probably worsened overall anxiety in a lot of patients. Now they are rarely prescribed.

arikr Jul 3, 2017 View on HN

Not MDMA, but correlational data exists for classic psychedelics: https://www.ncbi.nlm.nih.gov/pubmed/28443703

baby Jan 31, 2021 View on HN

Mdma is not a psychedelic. Have you tried it?

qwerty456127 Jan 12, 2018 View on HN

The only problem with MDMA is it is not legal in the majority of countries. Up to hundreds thousands (something less maybe, but still a lot) of people all over the world would gladly submit reports about their experiences of taking MDMA together with and without these substances (piracetam, magnesium, antioxidants etc) if this was not associated with risk of getting busted by the authorities. I have no doubt his advices would have been proven statistically then.

rpkoven Sep 25, 2019 View on HN

I’ve heard of the benefits of mdma therapy

zasdffaa Dec 6, 2022 View on HN

Not being flippant, but some MDMA. It makes a huge difference to my quality of life if used occasionally.

WalterGR May 4, 2025 View on HN

What's MDMA's addiction risk profile and therapeutic use potential vs. other "party drugs" such as - say - cocaine?

localfirst Aug 13, 2024 View on HN

MDMA triggers very bad depression wouldn't recommend itI think marijuana is a better alternative to MDMAAll in all I reject taking any drugs now.Just exercise and meditation to feel stoned.The mind is powerful, use it, don't use chemicals!