Supplement Regulation Issues

The cluster discusses the lack of regulatory oversight for dietary supplements in the US, highlighting problems like inaccurate labeling, contamination, dosage inconsistencies, and safety risks compared to pharmaceuticals.

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#824
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Keywords

e.g NADH US SSD OP labdoor.com www.fda wikipedia.org news.osu WTF supplements supplement ingredients ingredient fda drug pills active medicines dosage

Sample Comments

Angostura Jul 5, 2024 View on HN

Aren’t they normally sold as supplements’ not medicines, to circumvent regulations?

rceDia Jan 23, 2026 View on HN

Great resource for categories and research on supplements. Because supplements in U.S. are in the "wild west" of regulatory oversite, its important to know ingredient efficacy and ingredient purity. Consumer Labs (pay for subscription) offers some testing on selected products. Need to tweek "purchase from other market" -not all markets are "Out" as indicated.

JumpCrisscross Jul 2, 2023 View on HN

Is there a downside to deregulating them? (Like supplements.)

MBCook Jan 15, 2016 View on HN

It's all the supplements and other homeopathic exemption stuff that worries me. Not only do they not have to prove they're effect (at all, let alone more effective than the standard treatment), but they've had serious safety issues in the past. Ephedra is a classic example. Plus there are so many times people do tests that find supplements don't contain what they claim.

chana_masala Sep 6, 2021 View on HN

It's also unregulated and the actual dosage compared to the label can be wildly different, and can even be contaminated.

gnulinux Feb 25, 2019 View on HN

That happens all the time. Please check https://labdoor.com/ before buying any unregulated drug.

zrobotics Jun 17, 2018 View on HN

There is no oversight of supplements (at least in the US). You just have to trust the brand, because legally there's nothing stopping a supplement manufacturer from using entirely different ingredients from what is claimed.

dominotw Aug 22, 2022 View on HN

if you could tell the difference they would be called medicines not supplements.

dropden52 Jan 9, 2018 View on HN

Since vitamins and supplements are totally unregulated it could be that it doesn't actually contain any of the active ingredient it claims it does, thereby avoiding any legal issue.

skywhopper Jan 3, 2026 View on HN

I’m concerned you are overestimating the value of the certificate of authenticity you’re getting from your supplier. While you may be right that the compounds you intend to take can’t possibly be all that harmful, there’s a good chance what you’re getting may not be what you think, may not be entirely what you think, and likely contains other things that may be harmful, particularly over a longer period of time.