Gene Therapy for Deafness

Discussions center on a promising gene therapy trial restoring hearing in patients with genetic deafness, featuring excitement about potential cures, skepticism on efficacy and timelines, and hopes for broader applications.

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Keywords

e.g signonsandiego.com HN sciencemag.org signonsandiego.c CAR STRC nature.com ALS GJB2 treatment cure treatments therapy gene disease diseases years away cancer promising

Sample Comments

refracture May 14, 2024 View on HN

Even if a cure isn't likely this is still exciting.

leshow Dec 18, 2019 View on HN

Wow a "cure". Wouldn't that be nice. It's equally likely it could be used to develop a super expensive treatment of questionable effectiveness.

acdha Nov 24, 2013 View on HN

1. Wait until something ships before thinking it's changed anything. Medicine is littered with would-be wonder drugs which turned out to have critical shortcomings — if these were easy problems, they'd already be done by now.2. In many cases, new treatments don't help outside of the early stages — in the story you linked, the description suggests that the treatment wouldn't help someone who's already in an advanced stage of the disease. Great for the future, perhaps,

NotSammyHagar Nov 7, 2015 View on HN

This is an incredible medical advance, the old idea from at least the 70s actually working. It will take a long time until we can apply this to most diseases or conditions. There are so many different causes and interactions behind medical problems, even those that can be attacked by genetics + specially designed org like this. I'm sad my mom's cancer couldn't be treated by something like this.Live long enough, and we'll keep seeing amazing things!

simmerup Jul 18, 2025 View on HN

Damn, gene therapy is so promising too

zubairq Apr 7, 2019 View on HN

Amazing. Is this used to treat patients in the real world?

theGeatZhopa Nov 16, 2023 View on HN

Keep up the good work! Hope this method will be used in many other cases and diseases too.Having something that can't be unhave and all the therapies that worsen the subjective condition, I'm really happy for everyone could be helped with this!

msie Nov 26, 2015 View on HN

Finally! A treatment that's not 5-10 years away! I expect to see this therapy deployed widely any moment now. This should be front page news!

kobeya Mar 16, 2017 View on HN

Somebody has to be first to get a treatment. You don't really know whether it will work until you try it. Also mentioned in the article are the cases where treatments worked as they were supposed to or better.The headline is a bit misleading because the 3 ladies in question were already going blind. The treatment was supposed to reverse the disease but failed. You could write the same headline about other treatments that are considered safe enough to try: "3 patients killed by chemo

msie Oct 23, 2023 View on HN

Sounds like something promising that could lead to a therapeutic treatment.