Mouse Studies Skepticism

Commenters repeatedly question the applicability of research findings from mouse experiments to humans, emphasizing differences between mice and people and the poor translation of results.

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Keywords

MICE IN wikipedia.org yourgenome.org FYI KDS2010 mice mouse humans study rats studies human research translate experiments

Sample Comments

bluGill Jul 17, 2018 View on HN

In mice... Might or might not apply to humans.

I thought mice studies don't directly translate to humans..

2OEH8eoCRo0 Jun 27, 2024 View on HN

Mice aren't people. Small sample size- sounds like they used only 8 mice?

underyx Jan 7, 2024 View on HN

Probably yet another mouse experiment that doesn’t transfer to humans.

themitigating Jul 12, 2022 View on HN

This is covered everytime a study comes out, mice are similar to humanshttps://www.yourgenome.org/facts/why-use-the-mouse-in-resear...Your comment that 'you're not a mouse so this doesn't apply' is an overly simplistic conclusion based solely on a visual observation that is repeated on Hackernews so often there needs to be a bot that

GeoAtreides Jun 28, 2024 View on HN

no, of course not, we've been using them in experiments just for shits and giggleshttps://en.wikipedia.org/wiki/Laboratory_mouse#Limitations

calf Mar 1, 2024 View on HN

The abstract says they did mice experiments; so do they draw any conclusions for humans?

polishdude20 Dec 16, 2025 View on HN

They did it in a "mouse model" does that mean it wasn't even a live mouse?

auston Oct 31, 2020 View on HN

This! Mice are not quite the same as humans.

godelmachine May 10, 2018 View on HN

It's a well known fact that mice and humans promdominantly share the same genome, so this research should be taken with more than grain of salt, methinks.