Cannabis-Schizophrenia Link

The cluster debates the relationship between cannabis/marijuana use and schizophrenia or psychosis, including causation vs correlation, genetic predispositions, self-medication by those with mental health issues, and personal anecdotes of drug-induced episodes.

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Keywords

BiPolar ITT US McGrath www.who HN sciencedirect.com webmd.com news.bbc NMDA schizophrenia psychosis cannabis marijuana drugs episodes illness genetic symptoms mental

Sample Comments

jjawssd May 4, 2017 View on HN

Is it possible that psychotic people tend to self medicate more with it?

jeremiahbuckley Jul 17, 2024 View on HN

A user named observationist made a response to this post, but they responded to a troll, whose comment was nuked which removed their very valuable comment (I was responding to them at the time so I happened to have both in cache).observationist https://news.ycombinator.com/user?id=observationist original comment:Around 1% of people have schizophrenia. This holds over a lifetime - there's a

wildgift Sep 13, 2014 View on HN

As I understand it, things like schizophrenia are primarily hereditary, and the trauma pushes you over the edge. So, people with a family history of schizophrenia or related conditions shouldn't do these drugs.

tsotha Aug 9, 2013 View on HN

Why do you assume the schizophrenia was "likely induced by heavy marijuana use"?

annoyingnoob Jan 7, 2023 View on HN

https://www.webmd.com/schizophrenia/schizophrenia-marijuana-...

asveikau Jun 29, 2025 View on HN

It's important to know that the correlation can have some other cause. Like that people with predisposition to schizophrenia may seek out drugs.Keep in mind also the typical onset for schizophrenia is teenage years or early 20s in men, and is often later, up to early 30s in women. These are years you might experiment with drugs.

Throwaway42754 Jun 29, 2025 View on HN

I have schizoaffective disorder, induced by a bad trip from marijuana. It was like the 3rd time I had tried weed, and I naively took too much.For me psychosis feels like pattern matching going on extreme overdrive, while at the same time memory goes to shit. It's truly an awful illness, and what's worse is that the current medical treatments are bad. I've been fortunate enough where I can get by on a low dose olanzapine, but for many people they simply don't work at all.<p

idlewords Mar 20, 2019 View on HN

Don't many psychotic and schizophrenic people self-medicate with cannabis?

bjourne Oct 17, 2012 View on HN

Tobacco has anti-psychotic properties which can help to alleviate the effects of schizophrenia, which is one reason almost all schizo patients smoke. Alcohol on the other hand can make the condition worse because it has psychotic properties. Marijuana is both psychotic and anti-psychotic so how that will affect the patient is more unclear.

Circuits Aug 29, 2019 View on HN

"My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis." - that is a statement of fact so.. apparently not.