AlphaFold Protein Folding

Comments debate whether AlphaFold has solved the protein folding problem, its accuracy and limitations compared to traditional methods like Folding@home, and implications for biology, drug discovery, and science.

πŸ“‰ Falling 0.4x AI & Machine Learning
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Keywords

AI NN ML deepmind.com stanford.edu wikipedia.org nature.com VAE CRISPR NP protein folding structure proteins sequence fold prediction predict mutations researchers

Sample Comments

countvonbalzac β€’ Jun 18, 2024 β€’ View on HN

Is folding at home still relevant after alpha fold?

sidcool β€’ Mar 28, 2022 β€’ View on HN

AlphaFold. It's very near to cracking the 90% accuracy. And solving protein folding has huge long term benefits for himaniry

sam_lowry_ β€’ Jan 16, 2026 β€’ View on HN

Wasn't protein folding solved by our AI overlords once? Demis Hassabis? Alpha Fold?

hanniabu β€’ Sep 23, 2022 β€’ View on HN

Does this solve protein folding?

optimalsolver β€’ Jul 30, 2023 β€’ View on HN

Does the protein folding stuff from DeepMind count?

noplsbecivil β€’ Jul 29, 2022 β€’ View on HN

I wonder which proteins alphafold is having trouble with

aierou β€’ Jan 24, 2022 β€’ View on HN

Have you ever heard of AlphaFold?[0]: https://deepmind.com/blog/article/alphafold-a-solution-to-a-...

dyauspitr β€’ Sep 26, 2025 β€’ View on HN

Isn’t this a largely solved problem after Alphafold?

deeviant β€’ Nov 30, 2020 β€’ View on HN

The "science" of protein folding has a primary goal: to predict the structure of a protein given it's constituent parts.This is what alphaFold does, and it's been verified to produce results at an apparent accuracy at or above something like X-ray protein crystallography. The advances will come, after these results are validated and accepted by the scientific community as whole, simply when groups start using this technique to immediately access the structure of proteins t

fpordeig β€’ Aug 1, 2023 β€’ View on HN

This looks similar to the protein folding problem. Maybe an AlphaFold-like approach could work?