Hygiene Hypothesis Immunity

Comments focus on the hygiene hypothesis and how lack of pathogen exposure from hygiene, isolation, or modern living may weaken immune systems and increase risks of autoimmune diseases or poor responses to infections.

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#6079
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Keywords

MS EBV www.ncbi nlm.nih PMC2841828 PSA EVERYWHERE google.com PMC6334604 COVID immune immunity sick exposure response body disease diseases stronger rhetorical

Sample Comments

mewpmewp2 • Dec 26, 2023 • View on HN

You mean in terms of immune system not having been exposed to enough pathogens?

rvnx • May 15, 2021 • View on HN

Could it be because the immune system is busy with something else than fighting harmless agents ?

taneq • Mar 18, 2018 • View on HN

Sort of like exposure to pathogens / parasites can curb autoimmune diseases?

zkhalique • Oct 17, 2015 • View on HN

This ia a bit like making sure you don't get sick until your 20s and not letting your immune system develop robust responses to disease agents.

pmalynin • Aug 29, 2014 • View on HN

Frankly my point was more about the immune system.

w-j-w • Dec 12, 2020 • View on HN

You can't spread a disease if your immune system kills it on contact.

pertymcpert • Feb 2, 2020 • View on HN

What breaks their immune systems?

abstractspoon • Oct 13, 2025 • View on HN

Isn't that what my immune system is for?

im3w1l • Apr 27, 2023 • View on HN

This sounds like it would be very stressful on the immune system.

DANmode • Dec 16, 2025 • View on HN

PSA: healthy immune system humans are vastly over counted.