Natural vs Vaccine Immunity

This cluster debates whether natural immunity from prior COVID-19 infection provides equal, superior, or inferior protection compared to vaccine-induced immunity, including discussions on duration, effectiveness against variants, and the benefits of vaccination after infection.

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Keywords

pubmed.ncbi nlm.nih RBD nebraskamed.com CEO PubMed medrxiv.org HN COVID biznews.com immunity vaccine natural infection vaccinated covid infected antibodies vaccines immune

Sample Comments

sojournerc Nov 10, 2021 View on HN

Unless you've been infected already. Natural immunity is as good or better than the vaccine.

bingohbangoh Dec 14, 2021 View on HN

Weird, I thought that the natural immunity from COVID-19 wasn't as strong as the vaccine.

peter422 Dec 8, 2021 View on HN

There is little evidence right now that immunity through a natural infection is better than immunity from a vaccine.Given the strains circulating now I don’t think your concern is valid. Vaccines are better and less risky than having your naive immune system deal with covid. Maybe that will change with a future strain (though I’d bet against it), but it isn’t the case now.

13years Jul 28, 2021 View on HN

There is a good bit of data backing up that natural immunity is likely superior.https://www.biznews.com/health/2021/06/28/covid-19-vaccine-i...

aardvarkr Feb 10, 2022 View on HN

FYI Natural immunity provides a fraction of the immune response that being vaccinated does. People were getting reinfected with Covid after six months during the initial wave before any mutations cropped up.

js2 May 12, 2021 View on HN

The claim was "confirmed natural infection confers immunity equal to or greater than the vaccines is well established."I don't think that's true, certainly not to the point of “well established.”Here's another source:Which produces a stronger immune response: a natural infection or a vaccine?The short answer: We don’t know. But Covid-19 vaccines have predictably prevented illness, and they are a far safer bet, experts said.Vaccines for some pathogens, l

fmax30 Aug 27, 2021 View on HN

I meant the article said that the actual disease confers greater immunity than a vaccine.While that might be true, that immunity would only be good for one particular strain of the virus as opposed to the vaccine which provides you protection against a wider variety of strains.One can argue that the protection from the vaccine is better in the sense, that it protects you from a wider variety of Covid strains.Also, just so you know, that while the (mRNA) vaccine replicates protein, it is

gbear605 Sep 10, 2021 View on HN

Natural immunity is not as strong as the immunity provided by the vaccines and the immunity provided by both together is much stronger. Having already had COVID is no reason not to get vaccinated.

babesh Aug 26, 2021 View on HN

This says that natural immunity is 18x better. There is virtually no need for the vaccine.

Mvandenbergh Nov 29, 2021 View on HN

This is not the case. The protection from vaccination is both higher and more consistent than natural infection with Covid-19. The very best immunity observed is in people who have been naturally infected and subsequently vaccinated (I don't think any studies yet out that have tested the other way around). Those people produced antibodies which showed strong in vitro activity against even highly mutated and apparently immuno-evasive mutants and against other known coronaviruses.<a href="