Replication Crisis

The cluster discusses the replication crisis in scientific research, heavily referencing Ioannidis's 2005 paper 'Why Most Published Research Findings Are False' and issues like low reproducibility rates in psychology and other fields.

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Keywords

e.g US BS andrewgelman.com journals.plos nlm.nih JPA PMC1182327 HN papers.ssrn published findings studies research papers false 2005 study science replication

Sample Comments

mizzao Mar 2, 2016 View on HN

It's not satire; that's just the sad state of scientific experimentation. A similar finding was widely publicized for psychology studies:http://www.nature.com/news/over-half-of-psychology-studies-f...

dominotw Jul 30, 2016 View on HN

those studies are not 'science'. Have you heard of 'replication crisis'[1]? Also see the other top post currently on HN [2]..And, Yes universities are filled with idiots, egotists and scamsters with their own nefarious motives. How do you explain the absurd 90% hypothesis validation? [3]you have your own brain to observe and meditate on, why do you need some authority to tell you what to do.>If you want to prejudicially exclude research, don't claim to speak

lkbm Dec 27, 2016 View on HN

I assume he's alluding to Ioannidis's 2005 paper "Why Most Published Research Findings Are False"[0] and/or the replication crisis[1] in general.[0] http://journals.plos.org/plosmedicine/article?id=10.1371/jou...[1] <a href="http://www.nature.com/news/1-500-scientists-lift-the-lid-on-reprodu

dang Sep 25, 2024 View on HN

Related. Others?Why most published research findings are false (2005) - https://news.ycombinator.com/item?id=37520930 - Sept 2023 (2 comments)Why most published research findings are false (2005) - https://news.ycombinator.com/item?id=33265439 - Oct 2022 (80 comments)Why Most Published Researc

dependenttypes Sep 15, 2020 View on HN

Remember https://en.wikipedia.org/wiki/Why_Most_Published_Research_Fi...

xapata May 27, 2020 View on HN

"Most published research findings are false" (not reproducible)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/

dang Oct 19, 2022 View on HN

Related:Most Published Research Findings Are False (2005) - https://news.ycombinator.com/item?id=19016399 - Jan 2019 (39 comments)Why Most Published Research Findings Are False (2005) - https://news.ycombinator.com/item?id=18106679 - Sept 2018 (40 comments)Most Pu

lutorm Feb 8, 2010 View on HN

Funny link in one of the comments to a paper titled "Most scientific results are false". Does that apply to that paper, too?

Etheryte Nov 11, 2023 View on HN

Don't worry, it's not just this field, roughly 70% of medical studies are fake or severely flawed [0].[0] https://news.ycombinator.com/item?id=37572394

SubiculumCode Dec 20, 2021 View on HN

I'll break it down in a couple of bullet points.1. Science is hard.2. There is no such thing as a perfect study. Every method/methodology has weaknesses. Look for converging evidence across multiple studies which use different designs.3. Initial studies often do not have the funding needed to do things as optimally as possible in a single study, but they do provide evidence for ideas that can be pursued further.4. It is often socially safer to point out deficiencies than to