Cholesterol-Heart Disease Debate

We have the lowest average cholesterol ever and cardiovascular diseases are on the rise, so does it really make a difference?

If moving “high risk” patients to lower cholesterol levels does not decrease mortality, why bother with statins?

Title in HN is misleading. Original title refers to coronary artery disease and heart attack, which does not cover all heard diseases. Coronary artery disease is not a big problem now if you have finance to do angioplasty.

There's been increasing evidence that high cholesterol is a symptom of cardiovascular disease, not the cause.Editing because lots of people want sources.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513492/<a href="http://www.health.harvard.edu/blog/panel-suggests-stop-warning-about-cholesterol-in-food-201502127713

This is pure quackery. The cholesterol -> heart disease framework was developed by the Framingham studies (http://en.wikipedia.org/wiki/Framingham_Heart_Study) that showed a strong correlation between cholesterol and heart attacks and strokes. Now correlation does not equal causation but decades of subsequent studies have shown that cardiac event rates drop linearly with decrease in LDL (a for

I don't understand - what is the dumb meme? The link of high cholesterol to heart disease seems to be very well supported by numerous studies, and so are the benefits of reducing high LDL with diet or medication (statins).https://en.wikipedia.org/wiki/Cholesterol#Hypercholesterolem...According to the lipid hypothesis, elevated levels of cholesterol in

I'm surprised so many comments miss this. For heart disease it was a small effect size and not a statistically significant result. I.e. neither clinically nor statistically significant.

Cardiology tells you it doesn't.Do you really want to go down that road? https://www.youtube.com/watch?v=BKorP55Aqvg

Concentration of ApoB-carrying lipoproteins in the bloodstream as the driver of heart disease is one of the most strongly proven facts in medicine. Statins are proven to lower LDL (a close-enough substitute for ApoB in most situations) by about 30%. I can't look at the study now, but most likely it's a situation where patients' cholesterol has not been lowered enough by medication to make a meaningful difference. If you have an LDL of 160, statins aren't going to be sufficien

cholesterol values are read as corrolated to deseases we want to prevent, but not as a issue themselves.https://www.cdc.gov/cholesterol/index.htm> Too much cholesterol puts you at risk for heart disease and stroke, two leading causes of death in the United States.For instance if you have high cholesterol but clinically no artery or cardiac issues, lowering your cholesterol w