Nicotine vs Smoking

Comments debate the harms and addictiveness of nicotine itself versus smoking tobacco, emphasizing that nicotine alone is relatively benign like caffeine while smoking's dangers stem from combustion products and other chemicals.

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Keywords

PMC4553893 e.g wiley.com IMHO MJ nlm.nih PubMed nature.com MAO discovermagazine.com nicotine tobacco addictive smoking caffeine cigarettes harmful vaping addiction smoke

Sample Comments

danielbln Jul 31, 2023 View on HN

That's a function of nicotine, not of smoking. There are plenty of less terrible ways of getting nicotine into your system.

caseysoftware Jan 3, 2020 View on HN

According to the article, this is NOT smoking but nicotine itself.As written/described in the article, this would cover nicotine patches and gum to which your criticisms do not apply.

spdionis Feb 13, 2016 View on HN

Because it's 90% not about the nicotine.

eatitraw Dec 24, 2018 View on HN

IIRC, vaping pure nicotine might be less addictive than smoking tobacco because tobacco contains a ton of other chemicals

bufferout Feb 16, 2019 View on HN

Addiction aside (looking at you too caffeine)... how is nicotine bad exactly?

vidarh Aug 13, 2016 View on HN

Smoking appears to be more addictive than nicotine by itself. Pure nicotine in low enough doses has a fairly low addiction potential, and is mostly benign. But smoke, and you get the whole combination of other cigarette content, social pressure and ritual.

tomp Sep 18, 2019 View on HN

Actually, Nicotine (without the rest of the cigarette) actually probably isn't as bad (in particular, might not be addictive).https://www.gwern.net/Nootropics#nicotine

jacobolus Oct 7, 2021 View on HN

Nicotine is a stimulant, similar to other stimulants such as caffeine. The addictiveness in smoking apparently comes from (1) high dose absorbed rapidly, and (2) combination with other chemicals in tobacco and tobacco products.Nicotine addiction per se (or caffeine addiction) can be harmful to people, but the scale of harm is orders of magnitude away from the harms of smoking a pack of cigarettes a day. In small doses and in moderation, nicotine alone (e.g. taken as patch or gum) can be an ef

johnmaguire Jun 22, 2022 View on HN

Seems like nicotine is fine as long as it's combusted.

Lapsa Jan 1, 2026 View on HN

source please. afaik nicotine on itself is near negligibly harmful